Makuo chukwuover 5 years ago

Cyclopia

Baby born with one eyesocket which is a super rare birth defect known as Cyclopia! 😱 . . Doctors think the deformity could be a result of the mother taking medications during pregnancy or even having chemo treatment! . . . Cyclopia often results in a miscarriage or stillbirth. Survival after birth is usually a matter of hours only. This condition isn’t compatible with life. It isn’t simply that a baby has one eye. It’s a malformation of the baby’s brain early in the pregnancy. . . Cyclopia is a rare form of holoprosencephaly and is a congenital disorder (birth defect) characterized by the failure of the embryonic prosencephalon to properly divide the orbits of the eye into two cavities. Its incidence is 1 in 16,000 in born animals and 1 in 200 in miscarried fetuses! . . Cyclopia occurs when certain proteins are inappropriately expressed, causing the brain to stay whole, rather than developing two distinct hemispheres. This leads to the fetus having one optic lobe and one olfactory lobe, resulting in the eye and nose malformations of cyclopia. . . Genetic defects or toxins can misdirect the embryonic forebrain-dividing process. One highly teratogenic alkaloid toxin that can cause cyclopia is cyclopamine or 2-deoxyjervine, found in the plant Veratrum californicum (also known as corn lily or false hellebore).